★★★★★
"Transferring my prescriptions was easy, fast and they even called me to let me know it was ready for pick up. I will never go back to a chain pharmacy."
Chapel Hill's most trusted pharmacy
Where your
pharmacist knows
your name.
Locally owned. Community focused. Here for you.
Independently operated since 2013. Old-fashioned personal service paired with modern compounding, fast refills, and statewide shipping — from one pharmacy that genuinely cares.
10×
Best Pharmacy, Chapel Hill
4.9★
Google Rating
NC+FL
Statewide Compounding
🏆 Best Pharmacy · 10 Consecutive Years
State-of-the-Art Compounding Lab
PowderSafe hooded setup · LDN · LDBN · Pet meds · NC+FL
ED Medications from $1.00/tab
Sildenafil · Tadalafil · Discreet NC shipping
Walk-in Flu & COVID Shots
Mon–Fri 9am–3pm · No appointment needed
Custom Pet Medications
Flavored · Chewable · Transdermal · Statewide shipping
Chapel Hill Magazine · Readers' Favorite · 2026
Chapel Hill's Best Pharmacy —
10 consecutive years and counting.
Voted Best Pharmacy in Chapel Hill by Chapel Hill Magazine readers every single year since 2016. Not because we advertised the most — because our patients kept telling their neighbors. We are honored and grateful for every one of you.
10
Consecutive
Years
#1
Years
#1
Chapel Hill Magazine
Best of Chapel Hill 2026
Readers' Favorite
Best of Chapel Hill 2026
Readers' Favorite
4.9★
Google Rating
NC+FL
Compounding reach
2013
Chapel Hill roots
Accepts Most InsuranceYou pay your usual copay
Real Pharmacist AnswersCall 919-240-4084 · Reach a pharmacist fast
Free Curbside PickupNo additional cost for local patients
NC Statewide ShippingDiscreet · Fast · Reliable
10× Best PharmacyChapel Hill Magazine · Readers' Favorite
Our store — Southern Village, Chapel Hill
PowderSafe 700 Series hooded compounding lab
Pharmaceutical-grade ingredients
Every service you need from one pharmacy
that actually knows your name.
We accept most insurance plans. Reach a real pharmacist quickly — no endless loops, no runaround.
Custom Compounding
Hooded PowderSafe lab — one of the few in Chapel Hill. LDN, LDBN, dermatology creams, pediatric liquids, pain management gels, and more in custom strengths, forms, and flavors.
Explore compounding →Pet Medications
Gabapentin chewables, amlodipine suspensions, flavored liquids, and transdermal gels — custom veterinary compounding with fast turnaround and statewide NC shipping.
Pet compounding →Easy Refills & Transfers
Request refills via RxLocal, by phone, or in person. We call your old pharmacy for transfers — no paperwork needed on your end.
Refill online →Vaccines & Immunizations
Flu and COVID shots together in one visit. Walk-ins Mon–Fri 9am–3pm. School immunizations available. Book online or just walk in.
Schedule a vaccine →ED Medications
Sildenafil from $1.00/tab. Tadalafil from $1.00/tab. Significantly lower than chain prices. Valid prescription required. Discreet plain-package shipping to any NC address.
View pricing →Curbside & NC Shipping
Free curbside pickup for local Chapel Hill patients. Fast, discreet statewide NC shipping. Compounding also ships directly to Florida patients.
Find us →Compounding excellence
A real lab.
Pharmacy-grade precision.
Our dedicated non-sterile compounding department features a PowderSafe 700 Series hooded enclosure — one of only a handful in the Chapel Hill area.
- Low Dose Naltrexone (LDN) — 0.5mg to 4.5mg capsules, tablets, and liquid suspensions
- Low Dose Buprenorphine-Naloxone (LDBN) for medically refractory Restless Legs Syndrome
- Men's health: sildenafil/tadalafil troches, oxytocin lozenges, combination blends
- Dermatology: tretinoin/hydroquinone creams, nifedipine gels, scar and pruritus topicals
- Pain management: ketoprofen/lidocaine topicals, gabapentin/baclofen gels
- Pediatric: flavored antibiotic suspensions, dye-free and allergen-free preparations
- Veterinary: gabapentin chewables, amlodipine, atenolol suspensions, transdermal gels
- Weight management: bupropion/naltrexone, thyroid T3/T4 combinations, metformin
PowderSafe 700 Series · AirClean Systems · Chapel Hill, NC
NC+FL
States served
Non-sterile
USP-compliant
For Prescribers
E-prescribe, fax, or call. Filler adjustments available for patient sensitivities.
NCPDP# 3461225 · Fax 919-724-4568Transparent pricing
ED medications at honest prices.
Our sildenafil and tadalafil pricing is significantly lower than major chain pharmacies. A valid prescription is required.
Discreet plain-packaging shipping available to any North Carolina address.
Cash pricing only — excludes all third-party, commercial, federal and state insurance plans. Prescription required from any licensed provider.
Ask about ED medications →
Current Pricing
Rx Required · Cash OnlySildenafil 20mg & 25mg
Generic Viagra
$1.00/tab
Best deal: 90 tabs for $59
Sildenafil 50mg & 100mg
Generic Viagra — higher dose
$1.75/tab
Best deal: 30 tabs for $45
Tadalafil 5mg
Generic Cialis — daily
$1.00/tab
Best deal: 90 tabs for $59
Tadalafil 10mg & 20mg
Generic Cialis — as needed
$1.79/tab
Best deal: 30 tabs for $45
Discreet plain packaging · Ships to any NC address · Prescription required
Edward Leake
Owner & Pharmacist, RPh · 25+ Years Experience
25+ Years Experience
Licensed pharmacist · Compounding specialist
Compounding Expert
LDN, LDBN, veterinary, men's & women's health
Pharmacy Educator
Primary author of SVP's educational blog
Chapel Hill Local
Community roots since 2013 · Trained under Dave Smithwick
Call Ed's team directly
919-240-4084 · A real pharmacist, fast
Meet your pharmacist
Ed Leake, RPh —
the pharmacist who picks up.
"My goal is simple — completely exceed your expectations every single time. The kind of care that's almost impossible to find at a chain pharmacy."
Ed Leake took over Southern Village Pharmacy after working closely alongside longtime mentor David Smithwick for eleven months. With over 25 years of pharmacy experience, Ed is also the primary author of the pharmacy's educational blog.
When you call Southern Village Pharmacy, you may well speak directly with Ed. That's exactly the kind of pharmacy this is.
✓Licensed Pharmacist, RPh✓25+ Years Experience✓Compounding Specialist✓Chapel Hill Community Member✓Pharmacy Educator & Blogger
📞 Call Ed's team: 919-240-4084
What patients say
Trusted by Chapel Hill for over a decade.
4.9
Outstanding Google Rating
Best Pharmacy · 10 consecutive years
Best Pharmacy · 10 consecutive years
★★★★★
"There is a reason our family drives from Durham just for our prescriptions — the staff always goes the extra mile."
★★★★★
"Switched as my main pharmacy and will never go back. Friendly, takes time to explain everything, and truly helps."
Community roots
We're not just in this community.
We're part of it.
Every prescription filled here supports Chapel Hill — not a corporate shareholder.
Southern Village Stingrays
Platinum Sponsor since 2013
Porch School Foods for Schools
10+ years supporting CHCCS students
Super Cooper's Foundation
5+ years supporting pediatric brain cancer families
Tar Heel Express
Park & Ride hub for UNC sporting events
Common questions
Questions people ask us every day.
Or just call — a real pharmacist picks up every time.
Speak directly with a pharmacist
919-240-4084Toll-free: 1-844-617-2650
Mon–Fri 8am–6:30pm · Sat 8am–1pm
Do you accept my insurance?
Yes — we accept most prescription insurance plans. You pay your usual copay. Call us to confirm your specific plan is covered.
How do I transfer my prescriptions?
Call us or stop by. We contact your current pharmacy and handle the entire transfer.
Do you compound medications for pets?
Yes. Our hooded PowderSafe lab prepares custom medications for dogs, cats, and other animals.
Do you ship prescriptions across North Carolina?
Yes — statewide NC shipping with discreet packaging.
What is Low Dose Naltrexone (LDN)?
LDN is naltrexone compounded at 0.5mg–4.5mg. It cannot be purchased commercially.
Can I get flu and COVID shots at the same visit?
Yes. Both vaccines can be given together. Walk-ins welcome Monday–Friday 9am–3pm.
Has Southern Village Pharmacy really won Best Pharmacy 10 years in a row?
Yes. We have been voted Best Pharmacy in Chapel Hill by Chapel Hill Magazine readers every year since 2016 — 10 consecutive years, including 2026.
Can I speak directly with a pharmacist?
Absolutely. Call 919-240-4084 and a licensed pharmacist answers — no endless loops, no runaround.
Find us
Right in the heart of Southern Village.
Minutes from UNC Chapel Hill.
300 Market Street, Suite 114
Chapel Hill, NC 27516Next door to Village Pediatrics
Chapel Hill, NC 27516Next door to Village Pediatrics
Fax: 919-724-4568
E-Prescribe NCPDP# 3461225
Hours of Operation
Monday – Friday8:00 AM – 6:30 PM
Saturday8:00 AM – 1:00 PM
SundayClosed
Walk-in Vaccine Hours
Mon – Fri9:00 AM – 3:00 PM
Ready to switch to a pharmacy that
actually knows your name?
Locally owned. Community focused. Here for you.
Chapel Hill's Best Pharmacy — 10 consecutive years. Come see why.